Keywords:
Neoplasia, Cancer, Diagnostic procedure, MR, Oncology, Musculoskeletal soft tissue
Authors:
A. Neroladaki1, M. HAMARD1, L. C. C. Farracho1, E. Saiji2, M. Becker2, S. Boudabbous2; 1Genève/CH, 2Geneva/CH
DOI:
10.26044/essr2019/P-0066
Methods and Materials
We retrospectively evaluated 64 patients (figure 1) with histologically confirmed diagnosis of soft tissue sarcoma (STS) and pre-treatment MRI with T1,
fluid sensitive sequences and contrast enhanced images.
Two musculoskeletal (MSK) radiologists (16 years and 7 years of experience) analyzed several tumoral features such as size,
location,
intra-tumoral enhancement,
heterogeneity and internal low signal intensity components on T2,
peritumoral enhancement and the presence of a fascia tail.
The radiologists were blinded to the definitive diagnosis.
According to the French Federation of Cancer Centers grading system (figure 2),
tumors were categorized as low grade (grade 1) and high grade (grade 2-3) based on histologic specimens obtained by percutaneous/surgical biopsy or surgical resection.
Diagnostic accuracy was calculated for the 2 readers for every MRI feature separately and for combinations of features showing significant association with histology (p<0.05).
Associations between MRI features and high-grade sarcoma for the 2 readers were evaluated with Fischer’s exact test.