Congress:
EuroSafe Imaging 2017
Keywords:
Radiation therapy / Oncology, Computer Applications-Detection, diagnosis, PET-CT, CT, Thorax, Lung, Hybrid Imaging, Action 10 - EuroSafe Imaging Stars, Action 2 - Clinical diagnostic reference levels (DRLs), Action 8 - EuroSafe Imaging Stars network and data collection, Action 3 - Optimisation, diagnostic reference levels, image quality, Cancer, Neoplasia
Authors:
E. Neri, C. Giaconi, D. Volterrani
DOI:
10.1594/esi2017/ESI-0055
Description of activity and work performed
This is a prospective cohort study.
Since 2010 sixty-six follow-up PET/CT exams have been performed in 27 childrens and young adults (5-30 y; mean 23) affected by oncologic disease,
with elevated lung metastasis trophism (osteosarcoma,
Ewing’s sarcoma,
soft tissue sarcoma,
Wilms tumor).
CT scans were obtained with 120 kV,
100 mAs,
Noise Index 25,
row thickness 2,5 mm,
rotation time = 0,5s and DFOV = 38 cm; each serie was reconstructed with a CT lung algorithm and advanced statistical iterative reconstructions (ASIR; GE/Healthcare).
The measure DLP was 706,87 mGy × cm,
and effective dose 10,6 mSv.
A dedicated software (CT expo) was used to compare the radiation dose of a standard chest CT with the radiation dose of the chest PET/CT.
RESULTS
CT detection of lung nodules was effective with a negative predictive value (NPV) 96%,
positive predictive value (PPV) 92% with a sensitivity 82% and specificity 98%.
96 Normal 0 14 false false false IT JA X-NONE
The DLP value of the chest PET/CT was significantly lower (33%) of the standard of reference with 183 mGy x cm vs 275,9 mGy x cm.