2019 ASM / R-0112
Effectiveness of radiotherapy for Thyroid eye disease
Keywords:
Thyroid / Parathyroids, Eyes, CT, Radiation therapy / Oncology, Endocrine disorders
Authors:
E. Isdale, Z. Thotathil; Hamilton/NZ
DOI:
10.26044/ranzcr2019/R-0112
Methods and materials
- Retrospective review of radiation therapy and clinical records to identify and assess patients suitable for the audit.
- Assessment of patient symptoms both before (baseline) and then at least 6 months after radiotherapy (post) was assessed by using the NOSPECS symptom severity scoring system. Response to radiotherapy was assessed by [(baseline score - post score)/baseline score] Fig. 1
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Patients were treated to a dose of 20Gy/10fx, using 3D-CRT using parallel opposing fields, with target volume encompassing entire orbital contents. Anteriorly, non-divergent field edges were placed just behind the lenses. This was concurrent with pulsed methylprednisone.