Learning objectives
To provide an approach for recognising and categorising interstitial lung disease (ILD) and to illustrate common findings of ILD on computed tomography (CT).
Background
Interstitial lung disease (ILD) refers to a wide range of conditions that cause varying degrees of inflammation and fibrosis of pulmonary parenchyma [1]. ILD may be broadly subdivided by aetiology. Idiopathic interstitial pneumonia (IIP) encompasses a group of ILDs of unknown cause. ILD can be associated with connective tissue diseases such as rheumatoid arthritis and granulomatous diseases such as sarcoidosis. Exposure-related ILD includes asbestosis, silicosis and hypersensitivity pneumonitis.
The diagnosis of ILD requires a multidisciplinary approach. Supportive features include characteristic symptoms and signs such as...
Imaging findings OR Procedure details
IPF can be classified based on imaging findings on HRCT as outlined by the ATS/ERS/JRS/ALAT group [3]. Based on this, IPF can be categorised as:
Usual interstitial pneumonia (UIP)
Probable UIP
Indeterminate for UIP
Alternative diagnosis
There is moderate interobserver agreeance, even amongst thoracic radiologists, on how the ILDs are categorised. HRCT of biopsy-proven UIP also has atypical features in up to 30% of cases, so this guide is still being actively refined [3].
The UIP pattern (Figure 1) is characterised by honeycombing and traction...
Conclusion
This poster outlines the different imaging findings that are observed in ILD, including UIP, NSIP, OP, PPFE and hypersensitivity pneumonitis. Specific focus is paid to the UIP pattern given that timely diagnosis and early management with antifibrotics can improve its overall prognosis and life expectancy. A multidisciplinary approach is crucial in patient management, and imaging plays a vital role in this.
References
Kalchiem-Dekel O, Galvin JR, Burke AP, Atamas SP, Todd NW. Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History. Journal of clinical medicine 2018;7:476.
Ward J, McDonald C. Interstitial lung disease - An approach to diagnosis and management. Aust Fam Physician 2010;39:106-10.
Raghu G, Remy-Jardin M, Myers JL, Richeldi L, Ryerson CJ, Lederer DJ, Behr J, Cottin V, Danoff SK, Morell F, Flaherty KR, Wells A, Martinez FJ, Azuma A, Bice TJ, Bouros D, Brown...