Learning objectives
The aim of our study was to characterise the clinical-radiological-pathological spectrum of parotid oncocytomas inthe largest imagingseries to dateconsisting of 10 histopathologically provencases,
with an emphasis on the CT imaging features.
Background
Oncocytomas of the salivary gland which were first termed by Jaffè in 1932,
are benign epithelial tumours which occur most commonly in adults in their 6th-8th decades,1-6 although there is no clear gender predilection.3,
4,
6-9 These neoplasms are histologically composed of monotonous sheets of oncocytes,
epithelial cells named by Hamperl in 1931 which are characterized by an intensely eosinophilic and granular cytoplasm.
These metabolically altered epithelial cells accumulate numerous cytoplasmic mitochondria through the process of oncocytic metaplasia.1,
4,
5,
7,
10-12 Synonyms for this...
Imaging findings OR Procedure details
METHODS
A review of parotid tumours which were discussed at combined clinical-radiological-pathological sessions in our institution between January 2003 and November 2008 revealed 10 cases of histopathologically confirmed parotid gland oncocytomas.
The gender,
age at diagnosis,
clinical presentation,
type of surgical resection (superficial vs.
total parotidectomy) and recurrence during patient follow-up of all 10 cases were recorded retrospectively.
Institutional review board approval was obtained prior to the study.
All 10 cases were imaged using the TOSHIBA Aquilion multislice CT SCAN SYSTEM with the scan level...
Conclusion
DISCUSSION
Clinical features of oncocytomas resemble those of other benign and low-grade salivary gland tumours which makes clinical diagnosis challenging.
Patients typically present with a solitary,
slow-growing,
painless parotid mass,3,
4,
6,
8,
9,
16,
19,
20 similar to what was observed in our series.
All 10 cases in our series were diagnosed in adults in their 5th to 8th decades with a female preponderance.
Complete surgical excision of oncocytomas in the form of superficial or total parotidectomy depending on the location of the tumour...
Personal Information
CT Imaging Features of Parotid Gland Oncocytomas: A Study of Ten Cases
Tien Jin Tan,
Tiong Yong Tan
Department of Diagnostic Radiology,
Changi General Hospital,
Singapore
Corresponding author:
Dr Tan Tien Jin
Department of Diagnostic Radiology,
Changi General Hospital,
2 Simei Street 3,
Singapore 529889
Tel: (65) 6850 4948; Fax: (65) 6260 1703.
E-mail:
[email protected]
The data and images of this study were originally published as: T.J.
TAN,
T.
Y.
TAN.
CT Imaging Features of Parotid Gland Oncocytomas: A Study of Ten Cases and Literature...
References
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Hamperl H,
Benign and malignant oncocytoma.
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2.
Lee YYP,
Wong KT,
King AD,
Ahuja AT.
Imaging of salivary gland tumors.
Eur J Radiol 2008; 66: 419-436.
3.
Sciubba JJ,
Shimono M.
Oncocytic carcinoma.
Huvos AG.
Oncocytoma.
In: Barnes L,
Eveson JW,
Reichart P,
Sidransky D,
eds.
World Health Organization Classification of Tumors.
Pathology and Genetics of Head and Neck Tumors.
Lyon; International Agency for Research on Cancer Press: 2005; 237,
268.
4.
Capone RB,
Ha PK,
Westra WH,
et al....