Learning objectives
The staging of endometrial carcinoma is surgical,
however imaging plays a paramount role in evaluating and defining local extent of these tumours as well as in subsequent management and follow up. Several controversies existed with the previous International Federation of Gynecology and Obstetrics (FIGO) staging system,
which have now been addressed in the revised system introduced in 2009. MRI has an important role in local staging and imaging influences subsequent surgical management.
In this poster we will present the 2009 FIGO staging for endometrial carcinoma...
Background
Endometrial cancer is the fourth most common cancer in women. In the United Kingdom,
7,536 cases were diagnosed in 2007 and there were 1,741 deaths in 2008. Between 1971 and 2005 the there was a fall in mortality by 27% in the UK. The 10 year survival rate of endometrial carcinoma is 75% (1).
The majority of endometrial cancer occurs in postmenopausal women,
but up to 25% of cases may be premenopausal (2).
The lifetime risk of developing endometrial carcinoma is 1.7–2%,
and the incidence...
Imaging findings OR Procedure details
Imaging Techniques
Magnetic resonance imaging (MRI) is the most reliable imaging technique to define the depth of myometrial invasion and the degree of cervical involvement pre-operatively.
Transvaginal ultrasound (TVUS) is used for initial assessment of the endometrium in patients who present with abnormal uterine bleeding,
however MRI has been found to be more accurate then TVUS in assessment of myometrial invasion (12).
CT can be used to differentiate stage I and II (disease limited to the uterus) from stage III and IV (extra-uterine spread of...
Conclusion
The FIGO staging system for endometrial carcinoma has changed significantly in the 2009 modification,
with simplification of myometrial invasion,
cervical involvement,
peritoneal cytology and nodal disease.
Imaging is not considered to be part of formal FIGO staging for endometrial carcinoma,
but it has a vital role in the triage of patients with cytologically or histologically diagnosed endometrial malignancy,
both in terms of surgical selection and those likely to require adjuvant therapy.
Further research is required in DW-MRI for assessment of myometrial invasion and the use...
Personal Information
R Patel,
P Wylie,
R Patel,
N Bharwani.
Department of Radiology
Royal Free Hospital NHS Trust
Pond Street
London NW3 2QG
email address:
[email protected]
References
1.
Cancer UK. http://info.cancerresearchuk.org/cancerstats.
Accessed January 2011.
2.
Plataniotis G,
Castiglione M. Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis,
treatment and follow-up. Annals of Oncology (2010) 21:41-45.
3. Jemal A,
Siegel R,
Ward E et al. Cancer statistics. CA Cancer J Clin (2009) 59:225-249.
4. Sohaib SA,
Verma H,
Attygalle AD,
Ind TEJ. Imaging of Uterine Malignancies. Semin Ultrasound CT MRI (2010) 13:377-387.
5. Jelbert AE,
Bharwani N,
Rockall AG. The role of imaging in the management of endometrial cancer. CME Journel of Gynecologic...