Keywords:
Gastrointestinal tract, MR-Diffusion/Perfusion, PET-CT
Authors:
N. Gong, C. S. Wong, Y. C. T. Chu, J. Gu; Hong Kong/CN
DOI:
10.1594/ecr2012/C-1906
Purpose
Previous study focusing on the performance of DW MRI in GIST at diagnosis found several significant correlations between ADC parameters and SUV parameters,
which suggests the potential utilization of DWI as an alternative functional imaging tool to PET/CT in GIST diagnosis.
However,
no follow-up data has been presented.
Tumor treatment response assessment in GIST is utmost important.
In the present pilot study,
by comparing ADC parameters derived from DWI and SUV parameters derived from PET/CT for treatment response monitoring and response prediction,
we tried to find out whether DWI can serve as an alternative to PET/CT,
or at least provide quantitative measurements that are comparable to PET/CT for describing GIST lesion’s characteristics at follow-up.
In addition,
to improve the accuracy of the ADC parameters,
we novelly introduced a threshold measurement approach.
And a new parameter similar to TLG in DWI was proposed and studied for its potential role in representing the lesions’ functional and anatomical features as a whole.
In the present study,
we aim at exploring the potential usage of MRI in GIST patients for treatment response monitoring in addition to its diagnostic accuracy which has been achieved in previous works.