Keywords:
Gastrointestinal tract, MR-Diffusion/Perfusion, PET-CT
Authors:
N. Gong, C. S. Wong, Y. C. T. Chu, J. Gu; Hong Kong/CN
DOI:
10.1594/ecr2012/C-1906
Results
Table 1.Lesions’ treatment response in PET/CT and MRI
Response category
|
PET/CT
|
MRI
|
Size only
|
Size plus ADCmean
|
Size plus ADCmean_thr
|
Complete Response
|
44.4% (16/36)
|
44.4% (16/36)
|
44.4% (16/36)
|
44.4% (16/36)
|
Partial Response
|
47.2% (17/36)
|
13.9% (5/36)
|
33.3% (12/36)
|
41.7% (15/36)
|
Stable Disease
|
8.3% (3/36)
|
41.7% (15/36)
|
22.2% (8/36)
|
13.9% (5/36)
|
Kappa value
|
---
|
0.45
|
0.69
|
0.91
|
Table 2.Summary of lesions’ measurements at initial and follow-up imaging (n=20)
|
PET/CT
|
|
MRI
|
LD
|
SUVmax
|
SUVmean
|
TLG
|
LD
|
ADCmean
|
ADCmean_thr
|
TDI_thr
|
Diagnosis
|
6.96 ± 3.64
|
3.47 ± 1.50
|
3.47 ± 1.51
|
347.67 ± 582.92
|
6.27 ± 3.43
|
1.26 ± 0.30
|
0.93 ± 0.22
|
147.79 ± 190.28
|
Follow-up Imaging
|
5.96 ± 3.63
|
1.94 ± 0.47
|
1.38 ± 0.30
|
74.93 ± 84.64
|
5.48 ± 3.44
|
1.74 ± 0.29
|
1.26 ± 0.21
|
79.90 ± 107.85
|
P value
|
= 0.001
|
< 0.001
|
< 0.001
|
= 0.027
|
= 0.003
|
< 0.001
|
<0.001
|
= 0.005
|
Table 3.Correlation and linear regression between PET/CT measurements and DWI measurements
|
Pair of parameters
|
R square
|
P value
|
Linear regression
|
Initial Imaging
(n = 37)
|
ADCmean and SUVmean
|
0.154
|
0.016
|
SUVmean = -1.997 ADCmean + 5.786
|
ADCmean_thr and SUVmean
|
0.523
|
< 0.001
|
SUVmean = -4.270 ADCmean_thr + 7.587
|
ADCmean and SUVmax
|
0.146
|
0.020
|
SUVmax = -3.037 ADCmean + 8.862
|
ADCmean_thr and SUVmax
|
0.529
|
< 0.001
|
SUVmax = -6.698 ADCmean_thr + 11.811
|
Follow-up Imaging
(n=20)
|
ADCmean and SUVmean
|
0.535
|
< 0.001
|
UVmean = -0.767 ADCmean + 2.713
|
ADCmean_thr and SUVmean
|
0.916
|
< 0.001
|
SUVmean = -1.358 ADCmean_thr + 3.090
|
ADCmean and SUVmax
|
0.635
|
< 0.001
|
SUVmax = -1.292 ADCmean + 4.187
|
ADCmean_thr and SUVmax
|
0.761
|
< 0.001
|
SUVmax = -1.912 ADCmean_thr + 4.349
|
Change of Parameters
(n=20)
|
△ADCmean and △SUVmean
|
0.516
|
< 0.001
|
△SUVmean = 0.613△ADCmean + 0.265
|
△ADCmean_thr and △SUVmean
|
0.527
|
< 0.001
|
△SUVmean = 0.630 △ADCmean_thr + 0.276
|
△ADCmean and △SUVmax
|
0.467
|
0.001
|
△SUVmax = 0.565△ADCmean + 0.338
|
△ADCmean_thr and △SUVmax
|
0.500
|
< 0.001
|
SUVmax = 0.595 △ADCmean_thr + 0.343
|
△TDI_thr and △TLG
|
0.501
|
< 0.001
|
△TLG = 0.500 △TDI_thr + 0.489
|