Learning objectives
To be aware of the main etiologies of cerebral veinous thrombosis.
To become familiar with imaging techniques and findings of cerebral veinous thrombosis.
To learn about diagnostic pitfalls of cerebral veinous thrombosis.
Background
In this retrospective study we analyzed the clinical and the neuroimaging findings of patients with cerebral venous thrombosis collected at our hospital from January 2009 to December 2011.
The diagnosis of cerebral venous thrombosis was made by MR and CT parenchymal images or with various venographic techniques: unenhanced time-of-flight MR venography,
and contrast material– enhanced MR venography and CT venography.
I.
Pathophysiology:(Fig.
1)
Venous thrombosis is related to three factors commonly known as “Virchow’s triad” including:
Hypercoagulability
Hemodynamic changes (stasis,
turbulence)
Endothelial injury/dysfunction
The mechanism...
Imaging findings OR Procedure details
46 patients (33 women) with a mean age of 38,7 years were analyzed.
In our study The most frequent clinical pattern was headache (70%) followed by seizures (15 %) and focal neurologic deficits (12%).(Fig.
9)
The most frequent site of venous occlusion was superior sagittal sinus followed by lateral sinus.
Clinical Manifestations
Cerebral venous thrombosis has a wide spectrum of clinical manifestations and modes of onset that may mimic many other neurological disorders and lead to frequent misdiagnoses or delay in diagnosis.
1.
Headache:
The...
Conclusion
Cerebral venous thrombosis is a relatively uncommon but serious neurologic disorder.
Since the possible causal factors and clinical manifestations of thrombosis are many and varie.
Imaging plays a primary role in diagnosis.
References
1.
StamJ.Cerebral venous and sinus thrombosis: incidence and causes in ischemic stroke.
Adv Neurol2003; 92: 225–232.
2.
James L.
Leach et al.Imaging of Cerebral Venous Thrombosis: Current Techniques,
Spectrum of Findings,
and Diagnostic Pitfalls.
October 2006RadioGraphics,26,
S19-S41.
3.
Colin S.
Poon et al .Radiologic Diagnosis of Cerebral Venous Thrombosis: Pictorial Review.
AJR 2007; 189:S64-S75.
4.
Gustavo Saposnik et al.
Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association .
Stroke April 1,
2011 42:1158-1192.
5....