-To review the CT and MRI appearance of the cirrhotic liver.
-To describe thepathologic conditions that can mimic cirrhosis.
Cirrhosis is the end result of every chronic diffuse liver disease from various etiologies.
The most common causes are hepatitis B and C viral infection,
and non alcoholic fatty liver disease.Cirrhosis is pathologically characterized by distortion of hepatic architecture due to marked bridging hepatic fibrosis and regenerative nodule formation.
In this educational exhibit,
we describe the morphologic signs of cirrhosis,
and provide useful tips to recognize a cirrhotic liver and to differentiate the cirrhotic liver from other conditions that can mimic cirrhosis.
Findings and procedure details
A non invasive diagnosis of cirrhosis can be done at CT and MRI by identifying hepatic and extrahepatic signs of cirrhosis.
At earlier stages of cirrhosis,
the liver can appear normal or show only subtle heterogeneity.
With disease progression,
characteristic regional changes in hepatic morphology are seen,
such as hypertrophy of the caudate and left lobes and atrophy of the segment IV.
Enlarged hilar periportal space
An enlarged hilar periportal space (defined as a distance between the right portal vein and the posterior...
CT and MRI signs of cirrhosis can help radiologists make a non invasive diagnosis of cirrhosis and differentiate cirrhosis from its mimics.
Liver fibrosis -- from bench to bedside.
2003;38 Suppl 1:S38-53.
Enlargement of the hilar periportal space.
The right posterior hepatic notch sign.
Ferrucci JT Jr.
Diagnosis of cirrhosis based on regional changes in hepatic morphology: a radiological and pathological analysis.
Cirrhosis: modified caudate-right lobe ratio.