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Keywords:
Gastrointestinal tract, Oncology, CT-Quantitative, MR-Diffusion/Perfusion, Staging, Imaging sequences, Technical aspects, Cancer, Tissue characterisation
Authors:
S. Sudarski, T. Floss, U. Attenberger, S. O. Schönberg, T. Henzler; Mannheim/DE
DOI:
10.1594/ecr2017/C-2674
Aims and objectives
MRI is to date the reference imaging modality for diagnosing patients with suspected rectal cancer due to excellent soft tissue contrast.
With MRI,
tumor assessment of both morphology and functional information like tumor perfusion is possible.
However,
the additional value of MR perfusion regarding diagnosis,
therapeutic management or prognostic value is unclear and studies are disconcordant [1].
A weakness of MR perfusion imaging is the limited comparability of MR perfusion parameters due to high variability of signal intensity characteristics and lack of 3D angulation a-posteriori to data aquisition.
With the tremendous reduction of radiation dose of CT imaging,
dynamic volume CT perfusion has become feasible [2].
CT density measurements can be performed in a robust and reproducible manner,
due to almost linear HU density characteristics.
The aim of this study was to determine the reproducibility of the four quantitative CT perfusion parameters blood flow (BF),
blood volume (BV),
mean transit time (MTT) and permeability (PERM) assessed with dynamic volume perfusion CT (dVPCT) in patients with rectal cancer.