Keywords:
Genital / Reproductive system female, Oncology, Pelvis, MR, Ultrasound, MR-Diffusion/Perfusion, Imaging sequences, Contrast agent-intravenous, Staging, Cancer, Image registration, Neoplasia
Authors:
B. Olimov1, F. Kossov2, O. Kirillova2, M. Khulamkhanova2, V. Panov2, I. E. Tyurin2, N. Levchenko3, B. Dolgushin2; 1Moskow /RU, 2Moscow/RU, 3Moscow /RU
DOI:
10.1594/ecr2018/C-0188
Aims and objectives
Ovarian cancer is currently one of the most common forms of the cancer in gynecology - for about 3.6 % of all cases,
with the mortality for about 4,3 %.
In Europe it is the leading cause of death among gynecologic malignancies,
ranking fifth in incidence (exceeded only by breast,
colorectum,
lung and corpus uteri) and sixth in mortality (exceeded by breast,
colorectum,
lung,
pancreas and stomach).
An important reason for high mortality rates of ovarian cancer is the identification at late stages.
The diagnosis “ovarian cancer” establishes in advanced stage at the most part of patients mostly because of asymptomatic development of disease and/or because of nonspecific symptoms at early stages of lesion.
The incidental detection of adnexal mass is very common in clinical practice.
The clinical impact of defining is an adnexal mass benign or malignant is enormous.
If detected lesion carries a substantial risk of malignancy treatment should be performed at a special oncology center.
Women believed to have ovarian cancer usually require radical cytoreductive surgery followed by chemotherapy or alternatively neadjuvant chemotherapy followed by interval debulking.
Conversely women with benign adnexal masses may be either treated conservatively or undergo simple resection by a general gynecologist.
Thus,
the aim of our study is to differentiate malignant tumors from benign ones,
and to determine the surgical strategy by different MRI modalities: routine T1- and T2-Weighted Images (T1WI and T2WI),
Diffusion-Weighted Images (DWI) with apparent diffusion coefficient (ADC) maps and Dynamic Contrast-Enhanced MRI (DCE-MRI) and to clarify the diagnostic efficacy of these modalities with their simultaneous use in the diagnostics of ovarian tumor (OT).