Type:
Educational Exhibit
Keywords:
Neuroradiology brain, CT, MR, MR-Diffusion/Perfusion, Education, Patterns of Care, Education and training
Authors:
C. Vidal Cameán1, G. Calvo Arrojo2, S. Guerrero Vázquez2, V. Armesto Perez2; 1Lugo, Ga/ES, 2Lugo/ES
DOI:
10.1594/ecr2018/C-2018
Background
To understand the demylinating disorders,
first we have to know about normal WM: myelination begins early in the third month postpartum and the most rapid period of myelination occurring in the first two years of life,
the oligodendrocytes produce the myelin that covers the axons of neurons wich join the glial cells to be the main components of the normal WM.
The lipid content of myelin is extraordinarily high and in less quantity water,
a fact to consider in the MRI studies.
The diseases that affects the pattern of normal myelination can be acquired (demyelinating normal myelin is destroyed) or congenital (dysmyelinating,
abnormality in the myelin formation process).
The demyelinating disease is classiffied in different categories: inflammatory,
infective,
autoinmune,
vascular and toxic-metabolic.
Whith this brief introduction,
we can begin a systematic approach to the radiologic manifestations of some of this deseases.