Aims and objectives
Breast cancer size is one of the main prognostic factors and a determining indicators in the choice of surgical treatment planning.
The accuracy of the assessment of the tumor size through the use of diagnostic imaging,
is essential for a correct therapeutic planning.
Preoperative measurements of the breast lesions are commonly obtained with DM and/or US and,
in accordance with the European guidelines,
only in selected cases with MRI 1,2,
3,
4.
Recent imaging technique introduced as a complementary and/or additional to DM,
DBT seems...
Methods and materials
The institutional review board approved this retrospective study in which we reviewed 71 breast cancers in 60 patients waiving the requirement to obtain any informed consent.
All patients underwent DM,
DBT,
and MRI between January 2015 and March 2017,
before definitive surgery.
The patients had a mean age of 52.5 years (range,
34-71 years).
Patients undergone to neoadjuvant chemotherapy were excluded from the study.
All patients meeting the following inclusion criteria (approved by the local ethics committee) in accordance with the literature and the European...
Results
The agreement between the measurements performed with the individual imaging methods and the definitive histological examination is shown in Table 1.DM was the least consistent method with histological examination: 38 cases (53.5%) were concordant,
10 underestimated (14%) and 10 overestimated (14%); 13 lesions were not visible to DM (18.3%).
For lesions measuring 2 cm the concordance between DM and histological examination was 65.9%,
for tumors> 2 cm was instead of 39.1%.
The DBT had a concordance with the histological examination of 66.1% (47 cases); 8...
Conclusion
Accurate measurement of tumour size is essential for the preoperative staging of breast carcinoma,
in order to establish correct surgical treatment planning,
especially when breast-conserving surgery is being contemplated5.
Although the final histological examination is considered as the gold standard,
surgical and therapeutic decisions must be made on the basis of imaging,
mainly with conventional modalities (DM and US),
and supported by MRI in selected cases.
The US tecnique often underestimates tumour size,
even though it is especially useful in patients with dense breasts,
in...
Personal information
A.
Russo,
MD
Department of Radiology,Ospedale Monsignor Raffaele Dimiccoli,Viale Ippocrate 15,
I.
Barletta,
Puglia,
70051,
IT.
0883577111.
[email protected]
M.
Perri,
MD
Department of Radiology,Ospedale Casa Sollievo della Sofferenza,Viale Cappuccini 1,
I.
San Giovanni Rotondo,
Puglia,
71013,
IT.
0882410016.
[email protected]
F.
Cinelli,
MD
Department of Radiology,Ospedale Casa Sollievo della Sofferenza,Viale Cappuccini 1,
I.
San Giovanni Rotondo,
Puglia,
71013,
IT.
0882410016.
[email protected]
F.
Fiorentino,
MD
Department of Radiology,Ospedale Casa Sollievo della Sofferenza,Viale Cappuccini 1,
I.
San Giovanni Rotondo,
Puglia,
71013,
IT.
0882410016.
[email protected]
A.
Simeone,
MD
Department...
References
1.
Yang WT,
Lam WW,
Cheung H et al (1997) Sonographic,
magnetic resonance imaging and mammographic assessments of preoperative size of breast cancer.
J Ultrasound Med 16:791–797
2.
Dummin LJ,
Cox M,
Plant L (2007) Prediction of breast tumor size by
mammography and sonography – A breast screen experience.
Breast 16:38–46
3.
Sardanelli F,
Giuseppetti GM,
Canavese G et al (2008) Indications for
breast magnetic resonance imaging.
Consensus document “Attualità in
senologia”,
Florence 2007.
Radiol Med 113:1085–1095
4.
Sardanelli F,
Boetes C,
Borisch B et...
