Keywords:
Breast, Mammography, MR, Computer Applications-3D, Intraoperative, Outcomes, Cancer
Authors:
A. Russo1, M. Perri2, F. Cinelli2, F. Fiorentino3, A. Simeone2, G. Guglielmi4; 1Barletta/IT, 2San Giovanni Rotondo/IT, 3san giovanni rotondo, it/IT, 4Foggia/IT
DOI:
10.1594/ecr2018/C-2032
Results
The agreement between the measurements performed with the individual imaging methods and the definitive histological examination is shown in Table 1. DM was the least consistent method with histological examination: 38 cases (53.5%) were concordant,
10 underestimated (14%) and 10 overestimated (14%); 13 lesions were not visible to DM (18.3%).
For lesions measuring 2 cm the concordance between DM and histological examination was 65.9%,
for tumors> 2 cm was instead of 39.1%.
The DBT had a concordance with the histological examination of 66.1% (47 cases); 8 cases were underestimated (11.2%) and 8 overestimated (11.2%); 8 lesions were not visible (11.2%).
By dividing the concordance according to the dimensions found in the histological examination,
for lesions measuring 2 cm the concordance was 77.6%; for lesions> 2 cm it was 51.6%.
The MRI was the absolute method with the greatest concordance with respect to histology: in fact,
50 lesions,
equal to 70.4%,
were concordant,
6 (8.4%) underestimated and 12 (16.9%) overestimated.
3 lesions (4.2%) were not diagnosed with MRI.
For cases of lesions of 2 cm we had a concordance of 83.5% with histology; in> 2 cm instead it was 53.1%.
Overall,
among the three imaging modalities,
the differences between the concordances that were statistically significant (p <0.01) were between MRI and DM and between MRI and DBT.
The differences in concordance between DBT and DM were not statistically significant (p> 0.01).
As can be seen in Table 2 the correlation coefficient we obtained (R: 0.89) is comparable to the R: 0.86 value described in the study by Förnvik et al.12. The MRI in our work has proved to be the best method for the evaluation of the extent of infiltrating carcinomas,
although the DBT has obtained a value only slightly lower (R: 0.89).
In particular,
MRI confirmed,
in agreement with the literature [1-11],
the method with the highest correlation with the histological examination (R: 0.92),
but the DBT obtained similar values (R: 0 ,
89) thus allowing a similar preoperative staging.
The DM instead obtained lower values (R: 0.83) (Figure 1).