Keywords:
Thorax, Computer applications, Oncology, CT, CAD, Percutaneous, Computer Applications-3D, Screening, Cancer, Epidemiology, Neoplasia
Authors:
M. Jelitto-Gorska, A. Durawa, R. Dziedzic, P. Kalinowska, M. Piskunowicz, E. Szurowska, K. Dziadziuszko, W. Rzyman, M. Studniarek; Gdansk/PL
DOI:
10.1594/ecr2018/C-2834
Results
283 participants with nodules diameter >10 mm or with suspicious tumor morphology were enrolled to diagnostic work-up.
In 175 individuals spirometry was performed.
14 patients with performed spirometry were excluded because their original LDCT could not be acquired for retrospective evaluation.
Finally,
a total number of 161 patients were included in the analysis.
63 participants were lung cancer positive (LCP) and 98 lung cancer negative (LCN).
Both groups were similar according to gender (F/M: LCN 46/52; LCP 26/37,
p=0.52) and age (LCN: 60.5; LCP: 61.3,
p=0.50).
Significantly higher cigarette consumption in LCP group (44.4 pack-years vs 36.1 pack-years in LCN group,
p<0.01) was observed.
The mean size of the tumor in LCP group was 22.2mm and was significantly larger than in LCN group that was 15,0mm (p<0.01).
There were comparable number of COPD patients in both groups (LCN 48/98,
49%,
LCP 33/63,
52,4%,
p=0.75).
Mean FEV1/VC% expressed as a continuous variable was slightly lower in LCP patients (64.9%),
than in LCN group (67.7%),
but the difference was not statistically significant (p=0.23).
There was no significant difference in the emphysema extent between LCP and LCN.
There were slightly more emphysematous patients in the LCP group (59.8%),
than in LCN group (40.8%),
but the difference was not statistically significant (p=0.26).
The case was similar if we analyzed the severity of emphysema in LCP and LCN group.
No association between the type of emphysema and presence of lung cancer was observed.
The detailed data is presented in Table 1.