Keywords:
Cardiac, Arteries / Aorta, Vascular, CT, CT-Angiography, CT-Quantitative, Computer Applications-Detection, diagnosis, Contrast agent-intravenous, Arteriosclerosis, Metabolic disorders, Tissue characterisation
Authors:
A. Kokov, Y. Dyleva, N. Brel, O. Gruzdeva, V. L. Masenko, E. Belik, E. Uchasova, O. Barbarash; Kemerovo/RU
DOI:
10.26044/ecr2019/C-0082
Methods and materials
The study included 76 patients with clinical and laboratory signs of coronary heart disease (CHD),
the average age of which was 63±3,7 years - group 1.
Group 2 included 32 patients without clinical and laboratory signs of coronary artery disease,
the average age was 61±2.8 years.
Patients of both groups were comparable by sex and age.
All patients underwent multislice computed tomographic angiography (MSCTA) of coronary arteries using a 64-slice tomograph General Electric LightSpeed 64 with a nonionic iodine-containing contrast agent (iodine concentration of 350 mg/ml).
The thickness of the pericoronary adipose tissue (PCAT) at the level of the left coronary artery trunk,
proximal and middle third of the anterior descending (LAD),
circumflex (CX),
and right coronary (RCA) arteries was measured on the obtained images in a density window from -160 HU to -50 HU (Fig.1,
Fig.2).
All patients in both groups underwent coronary angiography (CAG) to determine the percentage and number of coronary artery stenoses.
In addition,
all patients were calculated body mass index (BMI),
obesity criterion,
according to World Health Organization recommendations,
were values above 30 kg/m2.
All quantitative indicators are presented in the form of a median and quartiles (Me [Q25; Q75]).
For all types of analysis,
the values p<0.05 were considered statistically significant.