The growing prevalence of obesity in the world poses new challenges for researchers. In the course of the studies, the endocrine function of visceral adipose tissue on the development and progression of cardiovascular diseases was proved [1]. Pericoronary adipose tissue refers to an ectopic fat depot with a local effect on the walls of the coronary arteries [2]. Despite the fact that there is still a debate about the role of pericoronarу fat tissue on the vascular wall, there are works of scientists demonstrating this...

The study included 76 patients with clinical and laboratory signs of coronary heart disease (CHD), the average age of which was 63±3,7 years - group 1. Group 2 included 32 patients without clinical and laboratory signs of coronary artery disease, the average age was 61±2.8 years. Patients of both groups were comparable by sex and age. All patients underwent multislice computed tomographic angiography (MSCTA) of coronary arteries using a 64-slice tomograph General Electric LightSpeed64 witha nonionic iodine-containing contrast agent (iodine concentration of 350 mg/ml). The...

Patients of both groups did not differ in obesity expressed by BMI: group 1 - BMI = 27,8 [25,4; 31,1] kg / m2, group 2 - BMI = 27,3 [24,9; 29,6] kg / m2, p = 0,061. According to the MSCT coronary angiography, the values ​​of thickness PCAT were significantly higher in patients with CHD (Fig.2). At the level of the left coronary artery trunk, thickness PCAT in the first group was 3,4 [3,2; 3,7] mm, while in the second group it was 2,9 [2,5;...

The use of MSCT-coronarography allows a quantitative assessment of the thickness of the pericoronary adipose tissue. The expression of pericoronary adipose tissue is significantly higher in patients with IHD. A quantitative estimate of the thickness of the pericoronary adipose tissue can be used to isolate a group of patients at high risk of developing and progressing of cardiovascular diseases.

Alexander N. Kokov, PhD, Head of Radiology Dept. ofInstitute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia [email protected] www.kemcardio.ru www.researchgate.net/profile/Alexander_Kokov www.scopus.com/authid/detail.uri?authorId=8934320600

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