Abdomen, Pancreas, Oncology, MR, MR-Diffusion/Perfusion, Diagnostic procedure, Imaging sequences, Tissue characterisation
F. Donati1, P. Boraschi1, F. Pacciardi1, R. Cervelli2, G. Tarantini1, C. Lombardo1, U. Boggi1, F. Falaschi1, D. Caramella1; 1Pisa/IT, 2Pisa, It/IT
Methods and materials
Thirty-five patients with pathologically confirmed solid pancreatic lesions (ductal adenocarcinoma,
n=18; endocrine tumour,
n=10; focal chronic pancreatitis,
n=7) underwent MR imaging at 3T-device (GE DISCOVERY MR750;GE Healthcare).
After T1 and T2-weighted sequences and MRCP,
imaging protocol included DW MRI using an axial respiratory-triggered spin-echo echo-planar sequence with multiple b-values (150,500,1000,1500 sec/mm²).
Multi-phasic CE-PW MRI consisted of a 3D T1w DISCO (differential subsampling with cartesian ordering) sequence repeated up to 5 minutes.
A dose of 0.1mL/Kg of Gadobutrolo (Gadovist,
Bayer HealthCare) with a 20mL saline flush was injected at a flow rate of 5mL/sec.
DW and CE-PW MR images were processed using a dedicated software (GeniQ; GE Healthcare) by two experienced reviewers in conference,
obtaining both diffusion map with fitted ADC value and perfusion map with perfusion curve and perfusion parameters (Ktrans,
for each pancreatic lesion.