Keywords:
Abdomen, Pancreas, Oncology, MR, MR-Diffusion/Perfusion, Diagnostic procedure, Imaging sequences, Tissue characterisation
Authors:
F. Donati1, P. Boraschi1, F. Pacciardi1, R. Cervelli2, G. Tarantini1, C. Lombardo1, U. Boggi1, F. Falaschi1, D. Caramella1; 1Pisa/IT, 2Pisa, It/IT
DOI:
10.26044/ecr2019/C-2928
Methods and materials
Thirty-five patients with pathologically confirmed solid pancreatic lesions (ductal adenocarcinoma,
n=18; endocrine tumour,
n=10; focal chronic pancreatitis,
n=7) underwent MR imaging at 3T-device (GE DISCOVERY MR750;GE Healthcare).
After T1 and T2-weighted sequences and MRCP,
imaging protocol included DW MRI using an axial respiratory-triggered spin-echo echo-planar sequence with multiple b-values (150,500,1000,1500 sec/mm²).
Multi-phasic CE-PW MRI consisted of a 3D T1w DISCO (differential subsampling with cartesian ordering) sequence repeated up to 5 minutes.
A dose of 0.1mL/Kg of Gadobutrolo (Gadovist,
Bayer HealthCare) with a 20mL saline flush was injected at a flow rate of 5mL/sec.
DW and CE-PW MR images were processed using a dedicated software (GeniQ; GE Healthcare) by two experienced reviewers in conference,
obtaining both diffusion map with fitted ADC value and perfusion map with perfusion curve and perfusion parameters (Ktrans,
Kep,
Ve,
IAUGC) value,
for each pancreatic lesion.