Learning objectives
To learn about the pathophysiology of tuberculosis in different body systems.
To illustrate the common and uncommon radiological manifestations of tuberculosis in different organ systems including disseminated multisystem tuberculosis.
To know about the sequelae / complications of tuberculosis.
Background
Tuberculosis is a multisystem disease with a spectrum of presentations and manifestations. It is a major cause of illness and is one of the top 10 causes of mortality worldwide. TB and related morbidity and mortality are on decline globally. However, the emergence of MDR TB and resurgence of TB among the immunocompromised, make TB a universal concern. South East Asia region attributes to one-third of the world’s burden of tuberculosis (1). TB primarily affects the respiratory system but is known to have propensity for...
Findings and procedure details
Tuberculosis is caused by mycobacterial species in the Mycobacterium tuberculosis complex. Itis transmitted via airborne droplet nuclei. A large number of patients infected with TB present with pulmonary complaints as the lungs are the most common site for the development of tuberculosis. Extra-pulmonary TB can occur either as a part of the pulmonary infection or as a late generalized manifestation of the spread of bacilli (Fig 1). Manifestations of tuberculosis can range from what looks like a simple infection to severe multisystem involvements with life...
Conclusion
Different modalities of imaging can be used for diagnosis, management and follow up of patients with tuberculosis. Knowledge of various imaging manifestations of tuberculosis in different systems can help us in early diagnosis and proper treatment of patients with tuberculosis and in reducing the complications associated with the disease.
Personal information and conflict of interest
K. Koirala; Kathmandu/NP - nothing to disclose N. P. Neupane; Bhaktapur/NP - nothing to disclose P. D. S. Pradhan; Kathmandu/NP - nothing to disclose R. K. Ghimire; Kathmandu/NP - nothing to disclose
References
1.World Health Organization. Global tuberculosis report 2013. World Health Organization; 2013.
2.Fanning A. Tuberculosis: 6. Extrapulmonary disease. CMAJ: Canadian Medical Association Journal. 1999 Jun 1;160(11):1597.
3.Fenton MJ, Vermeulen MW. Immunopathology of tuberculosis: roles of macrophages and monocytes. Infection and immunity. 1996 Mar;64(3):683.
4.Lee JY, Lee KS, Jung KJ, Han J, Kwon OJ, Kim J, Kim TS. Pulmonary tuberculosis: CT and pathologic correlation. Journal of computer assisted tomography. 2000 Sep 1;24(5):691-8.
5.Gambhir S, Ravina M, Rangan K, Dixit M, Barai S, Bomanji J. Imaging in extrapulmonary...