Keywords:
Performed at one institution, Cross-sectional study, Prospective, Cancer, Diagnostic procedure, Contrast agent-intravenous, MR, Breast
Authors:
N. M. E. M. Settein, S. Abdallah, M. abdel shaheed; Mansoura/EG
DOI:
10.26044/ecr2020/C-03252
Results
In our study, there were 29 malignant lesions; 16 lesions were positive ER, 20 lesions were positive PR and 15 lesions were positive HER2. (table 1).
There was a statistically significant higher proportion of positive ER and positive PR in mass lesions while non-mass enhancement lesions (fig. 1) showed higher proportion of positive HER2 (fig. 2) as detailed in (table 2).
Regarding the margins of mass lesions, HER2 was positive in half of the cases with irregular margin and in none of the cases with speculated margin. All cases with speculated margin (fig. 3) had an immunohistochemical profile of ER+ (fig. 4), PR+ and HER2- as detailed in (table 4).
There was no statistically significant difference regarding shape of the mass; either irregular or rounded cases along with distribution of the three receptors among mass lesions, as well as the enhancement pattern; either heterogeneous or homogenous. The only two malignant cases with homogenous enhancement were ER+ and PR+ and HER2- as detailed in (table 3 & 5).