Keywords:
Performed at one institution, Observational, Prospective, Cancer, Diagnostic procedure, MR, Lymph nodes, Head and neck, Head and Neck
Authors:
M. PENUGANCHIPROLU, R. Bansal , B. AGGARWAL, U. Mukherjee, H. Chaturvedi; NEW DELHI/IN
DOI:
10.26044/ecr2020/C-04285
Methods and materials
STUDY POPULATION: INCLUSION CRITERIA:
Patients of age more than 18years of either gender who are clinically diagnosed and biopsy proven cases of oral squamous cell carcinoma and willing to undergo Pre-operative MR Imaging and definitive surgery referred from the department of Onco-surgery/Oncology were included in the study.
STUDY DESIGN & DURATION
This study was a prospective observational study with sample size of 57 and 1.5 years duration after the clearance of scientific and ethical committees.
METHODOLOGY
Patients fullfilling the inclusion criteria underwent an MRI.
Imaging Techniques:
All MR imaging examinations were performed with a clinical 1.5T imaging unit (Siemens, Saket, New Delhi, India).
Patient is laid in supine position on MRI table and T1W images were acquired in all planes (axial, sagittal and coronal). The T2W images and diffusion weighted images were acquired in the axial plane. STIR images were acquired in the coronal and axial planes. The intravenous contrast used was Gadolinium.
METHOD OF MEASUREMENT OF OUTCOME
For radiological measurement: Axial gadolinium-enhanced T1-weighted sequence was used to measure depth of invasion for tongue and buccal sub-sites where tumours lie vertically and hence, reflected in a medial to lateral dimension. A horizontal line was drawn joining the tumour-mucosa junction at both ends of tumour (referred to as reference line) from which a perpendicular was drawn to the point of maximum tumour thickness. This is considered to represent tumour depth.
The involved cervical nodes and their levels was documented.
DATA ANALYSIS
• Results were analysed statistically including frequency and percentage.
• Measurements were compared between groups using paired students T- test.
• Statistical significance was determined with P - Values, P < 0.05 were considered statistically significant.