Type:
Educational Exhibit
Keywords:
Neuro, Neuroradiology brain, MR, Diagnostic procedure, Inflammation, Retrospective, Observational, Performed at one institution
Authors:
V. Viuniski1, D. Nakata2, J. �. Duarte1; 1Porto Alegre/BR, 2Sao Paulo/BR
DOI:
10.26044/ecr2020/C-14695
Findings and procedure details
In iron-sensitive GRE phase imaging in MS patients iron is present in non-phagocytosing, M1-polarized microglia/macrophages at the rim of chronic active white matter demyelinating lesions. Phase imaging may therefore visualize specific, chronic proinflammatory activity in established MS lesions and thus provide important clinical information on disease status and treatment efficacy in MS patients.
In light of determining which of those advanced imaging sequences could support the evidence of DIS, alongside with studies to standardize the use of the central vein sign as a marker for MS, our research center has been interested in other MRI findings in MS. In this pictorial study, we demonstrate the presence of what we believe to be non-haem iron deposits in different patients with MS through T2 SWI sequence.
We revised patients with diagnosed with Remittent Recurrent MS over the last 3 years that performed CNS MRI in a 3 T MRI scanner in our research center.
We analyzed and counted the number of total WM lesions on Flair WI and SWI magnitude and phase sequences.