Renal Cell Carcinoma: imaging and pathologic correlation

Congress:

ECR 2020

Poster Number:

C-15322

Type:

Educational Exhibit

Keywords:

Genitourinary, Kidney, Oncology, CT, MR, Biopsy, Diagnostic procedure, Cancer, Multidisciplinary cancer care, Pathology, Retrospective, Not applicable, Performed at one institution

Authors:

P. Correia¹, J. Lopes Dias², H. Quinto²; ¹Lisboa/PT, ²Lisbon/PT

DOI:

10.26044/ecr2020/C-15322

DOI-Link:

https://dx.doi.org/10.26044/ecr2020/C-15322

Fig. 3: Papillary RCC of the right kidney in a 58 year-old patient . Axial T2-weighted...

Fig. 2: Clear cell RCC of the right kidney in a 61 year-old patient. Abdominal CT scan...

Fig. 4: Photomicrograph (hematoxylin-eosin, x 100) of two surgically removed papillary...

Fig. 1: Clear Cell RCC of the right kidney in a 70 year-old patient. Axial...

Fig. 13: Metanephric adenoma of the right kidney in a 48 year-old patient. Coronal...

Fig. 6: Chromophobe RCC of the right kidney in a 77 year-old patient. Axial precontrast...

Learning objectives

To describe the imaging appearance of the most common renal masses. To pinpoint the imaging features that help in the differentiation between benign and malignant causes. To review the imaging parameters that allow the diagnosis of the main subtypes of renal cell carcinoma.

Background

The number of renal incidentalomas has been increasing in the last few decades as the number of imaging exams keeps on growing. Kidney tumors include a broad spectrum of histopathological entities described in 2016 by the World Health Organization [1] (Table1). Renal cell carcinoma (RCC) accounts for approximately 90% of the malignant renal tumors, of which 75% are clear cell, 7-15% papillary and 5% chromophobe subtype [2]. The remaining 10% includes a variety of uncommon, sporadic, familial carcinomas, rare mesenchymal tumors, neuroendocrine tumors, lymphoma, and...

Findings and procedure details

RENAL CELL CARCINOMA - CLEAR CELL SUBTYPE (CC-RCC) Clear cell is the most common subtype of RCC. Most of the cases are sporadic (95%)[3], but can be familial or associated with von Hippel-Lindau syndrome. Compared to chromophobe and papillary subtypes, CC-RCC has a poor prognosis, with a five-year survival of 50-60%[3].Multicentricity and bilaterality are rare, although it can be present in up to 5% of patients[3]. On computed tomography (CT), CC-RCC usually presents as a mass with an expansile growth pattern. Due to its hypervascularization,...

Conclusion

Kidney tumors include a broad spectrum of histopathological entities. Imaging provides essential information on differentiating and staging renal masses. Whenever it is possible, imaging should be primarily used to differentiate benign and malignant tumors. Some MRI features can also help to distinguish the different subtypes of renal cell carcinoma.

Personal information and conflict of interest

P. Correia; Lisbon/PT - nothing to disclose J. Lopes Dias; Lisbon/PT - nothing to disclose H. Quinto; Lisbon/PT - nothing to disclose

References

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