CT-guided-lung biopsy (CTLB) is a relatively safe and widely accepted procedure for the diagnosis and characterization of several focal lung pathologies, including benign and malignant lesions.[1,8,9]
With advances in CT imaging and the growing interest of lung cancer screening, an increased incidence of small lung cancer, especially small adenocarcinoma, has been reported, and the management of lung nodules is becoming increasingly challenging.[2-5] Although observation strategy or direct surgical resection could be proposed if cancer probability is respectively low or high, many decision-making algorithms include a...
Methods and materials
Data Collection: Prior to the biopsy, all patient had undergone a diagnostic CT chest scan. Based on these images, a retrospective analysis was performed. Lesion size, localization, morphology and distance from the pleural surface were recorded. The latter was evaluated by an expert interventional radiologist considering the optimal needle trajectory to avoid major vessels, interlobular fissures, visible bronchi and overlapping of bone structures.
SUV (Standardized Uptake Value) were taken from the PET report and a maximum value equal or less then 2.5 was considered the...
Technical success was considered when the tissue sample was deemed appropriate to asses a specific malignant or benign pathology. The overall technical success was 78% (n =250), 68% (n=218) malignant and 10% (n=32) benign. Technical failure occurred in 22% (71 pz) because of inadequate samples (blood cloth, necrosis, normal parenchima or insufficient material for diagnosis).
The mean session duration was 19 minutes and the average duration of needle position and sampling was 10 minutes. The average DLP for the CT fluoroscopy alone was 65,9mGy x...
The study was successful in identify those variables of the nodules that are more likely to determine a more laborious and complex procedure. Overall success rate of CTLB performed in our court are comparable to those reported in literature, even if it significantly varied between the different clusters of lesions we take in consideration. 
Personal information and conflict of interest
E. Ronconi; Rome/IT - nothing to disclose M. A. Tipaldi; Rome/IT - nothing to disclose T. Polidori; Rome/IT - nothing to disclose F. Laurino; Eboli/IT - nothing to disclose A. Pisano; Rome/IT - nothing to disclose A. Zolovkins; Rome/IT - nothing to disclose G. Orgera; Rome/IT - nothing to disclose A. Laghi; Rome/IT - nothing to disclose M. Rossi; Rome/IT - nothing to disclose
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