Genitourinary, Anatomy, Neuroradiology peripheral nerve, MR, MR-Angiography, Intraoperative, Segmentation, Cancer, Prospective, Experimental, Multicentre study
I. Pyatnitskiy1, O. A. Vorontsov1, R. Ovchinnikov1, V. Mitrokhin1, R. Marishin1, E. Kharlamov2, B. Aleksandrov1, S. Droupy3, V. Medvedev4; 1Moscow/RU, 2Oslo/NO, 3Nîmes/FR, 4Krasnodar/RU
Methods and materials
Our methodology includes 3 steps:
(1) MRI scanning of pelvis with four sequences: T2_TSE (AX, COR, SAG),
окT2 mapping (AX), T2_space ZOOMit (AX), T2_space_ SPAIR;
(2) image postprocessing to differentiate and map CN and another significant structures;
(3) 3D reconstruction of the differentiated nerves.
We started by finetuning these methodology on three volunteers and conducted 12 MRI studies using 3 Siemens MAGNETOM MRI scanners: Aera48 1.5T with two coils Body18, then Skyra48 3T with coil Body60 and finally using Prisma64 3T with coils Spine+Body18. Then, we applied the optimized protocol with identified parameters on 12 patients (Fig.1-2). As the result we obtained 14 3D models (Fig. 3-6).
In order to verify the quality of our 3D models and CN mapping we applied our methodology on cadaver material by first MRI scanning and constructing a 3D model for a cadaver, then histologically analyzing the nerves and blood vessels, and finally comparing the 3D model with the results of histology (Fig. 7-9).