Learning objectives
In this study, we aim to evaluate the relationship between maximum standardized uptake value (max.SUV) with the primary tumor size and its T-stage as well as patients’ age and sex. In addition, we try to suggest the equations between (max.SUV) and tumor size in patients with non-small cell lung cancer (NSCLC)
Background
Lung cancer is the most commonly diagnosed cancer; of which non-small cell lung cancer (NSCLC) accounting for approximately 80% of newly diagnosed lung cancer. The prognosis of lung tumors depends on early and accurate staging and the histopathological type of the tumor.[1]
Although CT scanning has long been the go-to imaging modality to stage lung cancer, it is hindered by many limitations and pitfalls. It may be unable to distinguish a tumor from atelectasis, does not reflect tumoral metabolic activity and gives no idea about...
Findings and procedure details
This cross-sectional study included forty patients, with (nine) females (22.5 %) and 31 males (77.5%). Ages ranged between 35 and 88 years with the mean age of 62.95 years ±10.01SD. The study included (25) 62.5% patients with adenocarcinoma, (12) 30% patients with squamous cell carcinoma and (30) 7.5% patients with large cell carcinoma The (T) staging of the described primary lung masses were: (9) 22.5% with T1, (11) 27.5% with T2, (14) 35% with T3 and (6) 15% with T4 primary mass staging. Figure (1)...
Conclusion
Discussion:
Computed tomography (CT) of the chest has been the workhorse for establishment of the precise anatomical and morphological information. Though, (FDG) PET/CT acquired an increased dependance for the diagnosis and staging of lung cancer.[7]
The metabolic activity represented by (FDG) uptake is now considered to be a prognostic factor in patients with lung cancer [7,8]. Meaning that patients with positive FDG-PET-CT results in treated lung cancer had a significantly worse prognosis than patients with negative results. [9]. In our study, we explore whether max.SUV...
Personal information and conflict of interest
S. M. I. Y. Shalaby:
Nothing to disclose
E. Darwish:
Nothing to disclose
M. Gamal:
Nothing to disclose
A. Rashad:
Nothing to disclose
E. Neri:
Nothing to disclose
References
Karam MB, Doroudinia A, Behzadi B, et al. Correlation of quantified metabolic activity in nonsmall cell lung cancer with tumor size and tumor pathological characteristics.Medicine (Baltimore). 2018;97(32)
Budak E, Çok G, Akgün A. The Contribution of Fluorine 18F-FDG PET/CT to Lung Cancer Diagnosis, Staging and Treatment Planning. Mol Imaging Radionucl Ther. 2018;27(2):73–80.
Hochhegger B, Alves GR, Irion KL, et al. PET/CT imaging in lung cancer: indications and findings.J Bras Pneumol. 2015;41:264–74.(2))
Zhu SH, Zhang Y, Yu YH, et al.FDG PET-CT in non-small cell lung cancer:...