Learning objectives
To review imaging findings in cancer patients that present with urgent complications.
To present an approach by systems for the understanding of oncological emergencies' imaging.
To provide imaging pearls that help the radiologist to diagnose them accurately and promptly.
Background
There has been an important increase in the incidence of cancer worldwide with a concomitant rise in the probability of developing oncologic complications. About 33% of cancers present with oncologic emergencies and 80% of clinical emergencies in cancer patients are secondary to direct complications [1]. Oncologic emergencies are defined as acute, life-threatening conditions that develop directly or indirectly by the disease or treatment [2]. We can classify these emergencies into metabolic, hematologic, and structural [Fig 1]. Structural emergencies are the entities in which the radiologist...
Findings and procedure details
A.CENTRAL NERVOUS SYSTEM
1.CEREBRAL HERNIATION
Mass effect from tumor lesions or vasogenic edema are the two main causes of cerebral herniation [3,4]. [Fig 2] Slow growing tumors can produce minor symptoms, unlike fast growth lesions that produce sudden neurological deficit and high intracranial pressure.
Herniations may be supratentorial or infratentorial; the key to identify them is to define brain tissue displacement by looking at the midline, ventricles, and cisterns. It’s important that the radiologist reports these entities since they may have certain specific complications. [Fig...
Conclusion
Knowledge of oncological emergencies is key for accurate interpretation of images in cancer patients. Computed tomography is the study of choice in cancer patients with abdominal and thoracic complaints due to its availability, rapidness, and non-invasive approach. For the evaluation of the central nervous system the preferred image is MRI since it gives the most accurate depiction of anatomy and tissue characterization.
Personal information and conflict of interest
M. A. Aranda Hernández:
Nothing to disclose
D. A. Guerrero Gomez:
Nothing to disclose
N. Plata:
Nothing to disclose
R. E. Guatibonza:
Nothing to disclose
W. Aponte:
Nothing to disclose
References
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Bosscher MRF, van Leeuwen BL, Hoekstra HJ. Current Management of Surgical Oncologic Emergencies. 2015. PLoS ONE 10(5): e0124641. doi:10.1371/journal.pone.0124641
Landis SH, Murray T, Bolden S, et al. Cancer statistics. CA Cancer J Clin 1999;49(1):8–31, 31.
Smedby KE, Brandt L, Backlund ML, et al. Brain metastases admissions in Sweden between 1987 and 2006. Br J Cancer 2009;101(11):1919–24
Chamberlain MC. Carcinomatous meningitis. Arch Neurol 1997;54(1):16–7.
Chamberlain MC. Neoplastic meningitis. Oncologist...