Keywords:
Cardiac, MR, Imaging sequences, Ischaemia / Infarction
Authors:
A. Damascelli, F. De Cobelli, A. Esposito, M. Cava, G. Benedetti, A. Durante, A. Colombo, P. G. Camici, A. Del Maschio; Milan/IT
DOI:
10.1594/ecr2013/C-1057
Methods and Materials
We enrolled 23 consecutive patients with ST-elevation Myocardial Infarction (STEMI) within 12 hours of symptom onset,
who underwent PCI.
In PCI studies NR was defined as TIMI grade<3 and/or blush grade<2 post-PCI.
The exclusion criteria for CMR were: history of ischemic cardiomyopathy with left ventricular ejection fraction (LVEF) <35% before the infarction; age <18 o >80 yrs; BMI >35; ICD or pacemaker holders; contraindication to MR and contrast medium.
The CMR was performed on a 1.5 T magnet with the assessment of Cine sequences (BFFE- Breath Hold,
10-12 slices,
thk 8mm) for the evaluation of volumes and systolic function,
STIR (T2 IR TSE,
10 slices,
thk 8 mm) for oedema identification,
volumetric perfusion (T1 FFE-Breath Hold during,
8 slices,
2 stack,
10 thk) acquired during the 1st contrast injection (half dose of Gadobutrol-0.2 mmol/kg) to identify MVO and Early and Late Enhancement (3D IR TFE,
20 slices,
thk 5) acquired 4 and 10 minutes after 2nd contrast injection,
for assessment of infarct size and MVO (see fig.
3)
CMR criterion of NR was the lack of signal within areas of enhancement in FPP-sequences and/or in early and late- enhancement sequences.
We used a semi-automatic dedicated software for the elaboration of MR (see fig.
4).