Aims and objectives
Syntax score is an algorithm for grading coronary artery disease (CAD) and includes anatomical components,
such as: total occlusion,
bifurcation,
the presence of thrombus,
calcification,
the condition of small blood vessels.This assessment evaluates the risk of coronary disease occurrence and adverse cardiovascular events after percutaneous or surgical revascularization.
Such an assessment of CAD helps to better predict the risk of new cardiovascular events after percutaneous or surgical revascularization.
Therefore the objective of this study was to identify the relationship between the severity of coronary angiographic...
Methods and materials
Patient population: The number of patients examined was 51,
average age 60 ± 10,
who,
due to acute myocardial infarction with ST elevation (STEMI),
underwent a PCI.Immediately after the intervention and 6 months later,
echocardiographic examinations of anatomical and functional parameters of the left ventricle were carried out,
via the left ventricle mobility index.In the second examination,
the patients were asked to describe their health condition and the occurrences of cardiovascular disorders were monitored (cardiac death,
infarction,
heart failure,
revascularization,
or cerebrovascular stroke).
The study...
Results
The Syntax score average value was 14.7 ± 6.9.Low values (<22) were present in 42 patients,
mean value in 9 patients,
and no patient had values higher than 33.
Side cardiovascular events were recorded in 7 patients,
where 2 patients had repeated infarction and revascularization,
and 5 patients developed cardiac weakness.None of the patients died.There was no significant correlation between Syntax score and left ventricle remodeling or the occurrence of cardiovascular disorders.
Adverse cardiovascular events were associated with Killip class ((r=-0.269,
p=0.056),
left ventricular ejection...
Conclusion
In the group of patients with myocardial infarction who were treated with primary percutaneous intervention,
there was no correlation between the parameters expressed with angiographic Syntax score and left ventricle remodeling or the occurrence of cardiovascular disorders.
The results of previous studies that have recently shown remarkable prognostic significance of Syntax score cannot be extrapolated to patients with acute coronary syndrome and lower Syntax score.
Further studies are needed to address these concerns.
Personal information
D.
Petrovic,
MD
Department of Diagnostic Imaging,
Center of Radiology and MRI,
Clinical Center of Serbia,
University of Belgrade,
School of Medicine,
Pasterova 2,
Belgrade 11000,
Serbia.
Phone: +381648742761
email:
[email protected]
References
1.
Sianos G,
Morel MA,
Kappetein AP,
et al.
The Syntax score: an angiographic tool grading the complexity of coronary artery disease.
Eurointervention 2005;1:219-27.
2. Valgimigli M,
Serruys PW,
Tsuchida K,
et al.
Cyphering the complexity of coronary artery disease using the Syntax TM score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous corobary intervention.
Am J Cardiol 2007;99(8):1072-1081.
3.
Serruys PW,
Morice MCM,
Kappetein P,
et al.
Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease.
N...