Keywords:
Haematologic, Nuclear medicine, Hybrid Imaging, PET-CT, Molecular imaging, Lymphoma
Authors:
K. Paddubny, S. Kharuzhyk, A. Dziuban, O. Baranovski, E. Zhavrid; Minsk/BY
DOI:
10.1594/ecr2018/C-2030
Conclusion
1.
The high reproducibility of the Deauville categories established by different physicians was proved in 18F-FDG PET/CT studies performed in patients with lymphoma after ChT,
which is consistent with data from other studies [6].
2.
The non-specific 18F-FDG accumulation in organs and tissues (sarcoidosis,
inflammatory foci in the lungs,
reactive lymph nodes) can lead to false positive PET findings.
Diffuse 18F-FDG accumulation in the bone marrow may be a result of its activation after ChT and shouldn't be regarded as a lesion [2].
3.
PFS for category D 3 was 57% and didn’t differ significantly from the categories D 4-5.
Therefore,
in the category D 3 it’s recommended to conduct additional diagnostic studies to determine the activity of residual lesions,
to consider indications for additional treatment or more frequent monitoring is needed.
4.
SUV values are currently recommended as an addition to visual analysis [4] and also can be used as a prognostic factor.