Keywords:
Haematologic, Nuclear medicine, Hybrid Imaging, PET-CT, Molecular imaging, Lymphoma
Authors:
K. Paddubny, S. Kharuzhyk, A. Dziuban, O. Baranovski, E. Zhavrid; Minsk/BY
DOI:
10.1594/ecr2018/C-2030
Methods and materials
This is a retrospective study of 89 patients with lymphoma who underwent whole body (WB) PET/CT after completion of ChT during 2015-2017 in Republican Center of Positron Emission Tomography.
Hodgkin lymphoma (HL) occurred in 34 people,
non-Hodgkin lymphoma (NHL) in 55.
All patients were observed for at least 6 months after PET/CT.
The interval from the completion of ChT until the PET/CT was 41±29 days.
Preparation of the patient included fasting for at least 6 h and restriction of physical activity during the day before the study.
Blood glucose level before 18F-FDG administration shouldn’t be above 8.3 mmol/L [1].
PET/CT was performed from the base of the skull through the proximal femurs 66±20 min after 18F-FDG injection (305±57 MBq intravenously),
4 minutes emission scan per bed position.
Interpretation of PET/CT studies was performed using a 5-point Deauville scale.
Deauville (D) categories established during routine clinical interpretation and independent retrospective review were compared.
The final category was established by consensus.
In accordance with international recommendations categories D 1-3 were considered negative - complete metabolic response (complete tumor regression),
categories D 4-5 - positive (incomplete regression) [2-5].