Percutaneous Transhepatic Biliary Drainage (PTBD) is an established image-guided procedure which leads to the drainage of the obstructed bile duct system. PTBD main indications include decompression of intra and extrahepatic biliary ducts in case of malignant or benignant obstruction, cholangitis, the decrease serum bilirubin before starting chemotherapy, biliary stent placement [1-3]. Given the main palliative nature of PTBD, it is obvious that besides survival benefits, Health-Related Quality of Lifeaspects should represent a crucial point. After the PTBD, the relief of obstructive symptoms, especially pain and...

Study design: in this single centre prospective randomized study, 77 patients underwent PTBD for malignant obstructive jaundice from February 2017 to April 2018. As inclusion criteria to participate to the study we set: no age and gender limitation, imaging studies confirming the presence of distal malignant bile duct obstruction, hilum stricture, patients affected from surgically unresectable neoplasm, failed endoscopic treatment, US-guided puncture of biliary tree considered indifferently feasible from the right or left side. We excluded patients who refused to participate to the study, patients...

Patients characteristics: 63 patients were considered eligible to participate in the study and underwent PTBD via left or right access randomly selected. Some patients (n=3) didn’t complete the questionnaire properly and for this reason, were excluded. Final participants patients were 60 (n=30, subgroup A - PTBD right approach; n=30, subgroup B – PTBD left approach) (Fig 2). The study population includes 34 men and 26 female. There was no significant difference in gender and age between the two subgroups (Tab 3). The aetiology of malignant...

The purpose of this study was to compare Quality of Life in patients who underwent PTBD via right versus left access when both accesses were feasible. Our results showed highly significant difference related to pain, reported higher in patients who underwent PTBD via right access (p< 0.001). The continuous stimulation of intercostal nerves could play a crucial role, and the additional independent questions about localizing pain confirm that intercostal pain is the main localization when the PTBD is performed via right access (Tab 4). Respiratory...

Davide Giuseppe Castiglione, MD, Radiology resident at University of Palermo. Dipartimento di Biopatologia e Biotecnologie Mediche, AOUP P. Giaccone, Università degli Studi di Palermo Via del Vespro 127, 90127 Palermo, Italy Phone : +39 3278139979 e-mail: [email protected]

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