Learning objectives
The purpose of this exhibit is:
1. To illustrate imaging method of whole body high spatial resolution contrast-enhanced 3D volumetric-interpolated breath-holdexamination on the compressed sensing technique (CS-VIBE)
2. To illustrate whole body fusion imaging between diffusion-weighted imaging (DWI) and CS-VIBE (CS-FDWI)
3. Review of the detection of metastatic lesions using whole body CS-FDWI.
Background
The accurate detection of metastatic and recurrent lesions for cancer patients play an important role in clinical care. Imaging is fundamental to evaluation and management of cancer patients. While CT and PET are well established imaging modalities for cancer and lymphoma, the number of serial examinations required throughout the course of therapy and subsequent surveillance has prompted concern regarding cumulative ionizing radiation exposure(1).
Whole-body MRI, by enabling wide field-of-view imaging withhigh spatial and contrast resolution to provide robust soft-tissue characterization in the absence of ionizing...
Findings and procedure details
Protocol and imaging technique of whole body MRI
Institutional Review Board approval and informed consent from all patients performed 1.5T and3T whole body MRI with CS-VIBE were obtained.
Whole body MRI was performed at 1.5T and 3.0T MR system with 48 or 64 independent receiver channels and a total imaging matrix system.
Prior to the examination, a 22 gauge intravenous catheter was placed into an antecubital vein of arm to facilitate contrast medium injection. No bowel preparation, air insufflation, or intravenous antispasmodic agents were used....
Conclusion
Whole body CS-VIBE is a new method which acquires high resolution contrast-enhanced images. Furthermore, CS-FDWI provides both improved lesion conspicuity and high spatial resolution images.
Whole body CS-VIBE and CS-FDWI may be acceptable diagnostic tool for detection of primary cancers and metastases, and surveillance of cancer patients.
Personal information and conflict of interest
H. Horikoshi; Ota/JP - nothing to disclose A. Okayama; Ota/JP - nothing to disclose T. Kawakami; Ota/JP - nothing to disclose N. Oya; Ota/JP - nothing to disclose T. Akiyoshi; Ota/JP - nothing to disclose K. Maruyama; Tokyo/JP - nothing to disclose M.D. Nickel; Erlangen/DE - employee at Siemens
References
(1) Gottumukkala RV, Gee MS, et al. Current and emerging roles of whole-body MRI in evaluation of pediatric cancer patients. Radiographics 2019;39:516-534.
(2) Villani A, Shore A, et al. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. Lancet Oncol 2016;17(9):1295–1305.
(3) Eutsler EP, Khanna G. Whole-body magnetic resonance imaging in children: technique and clinical applications. Pediatr Radiol 2016;46(6):858–872.
(4) Davis JT, Kwatra N, Schooler GR. Pediatric whole-body MRI: a review of current imaging...