To illustrate the different imaging findings of intracranial tuberculosis,which is challenging to diagnose with laboratory results and clinic examination. To be familiar with complications of intracranial tuberculosis.

Tuberculosis(TB) is an infectious disease caused by Mycobacterium tuberculosis,one of the top 10 causes of death in the world.Approximately a quarter of the world’s population is infected with M. tuberculosis and consequently at danger of developing TB disease[1].Central nervous system (CNS) involvement is seen in 2%-5 % of patients with TB and the most common form of tuberculosis causing mortality and morbidity[2]. The underlying mechanism of intracranial TB is the rupture of small TB lesion(Rich focus) that is disseminated by hematogenous spread to subpial or...

Intracranial TB is becoming more sophisticated and atypical due to multi-drug resistance. MRI Protocol Any MRI of patients suspected of intracranial tuberculosis should include axial precontrast T1W,T2W,FLAIR,diffusion-weighted images sequence(DWI) GRE/SWI and postcontrast T1W scans in all three plans.Magnetic resonance angiography(MRA) and magnetic resonance venography(MRV) may be added in patients with suspected vascular complications. The Spectrum of Intracranial TB A-MENINGEAL 1-Leptomeningeal 2-Pachymeningitis B-PARENCHYMAL TUBERCULOSIS 1-Tuberculoma 2-Cerebritis 3-Abscess 4-Rhombencephalitis 5-Encephalopathy A-MENINGEAL TUBERCULOSIS 1-Tubercular Leptomeningitis Tuberculous meningitis(TBM) is the most common manifestation of CNS TB and occurs frequently...

CNS TB is the most common form of tuberculosis causing mortality and morbidity.Early diagnosis and treatment of CNS TB are important to prevent these consequences. Familiarity with the different imaging presentations of CNS TB is crucial to timely diagnosis. Bear in mind that tuberculosis can be seen everywhere due to immigration.Hence, every radiologist should be familiar with various radiologic features of intracranial tuberculosis.

M. Alacagöz Sorkun; Istanbul/TR - nothing to disclose S. Erdemli; Istanbul/TR - nothing to disclose B. Atalay; Istanbul/TR - nothing to disclose M. B. Eser; Istanbul/TR - nothing to disclose B. Baysal; Istanbul/TR - nothing to disclose

World Health Organization Global tuberculosis report 2019.Available at https://www.who.int/tb/global-report-2019 Muhammad Azeemuddin, Amna Alvi, Raza Sayani, Misha Khalid Khan, Salman Farooq, M. Asim Beg, Safia Awan, Mohammad Wasay. Neuroimaging Findings in Tuberculosis: A Single-Center Experience in 559 Cases.J Neuroimaging.2019 Sep;29(5):657-668 Chen YZ,Sun LC,Wen YH,Li ZW,Fan SJ,Tan HK,Qiu M,Pan ZY,Li Q,Zhao YZ,Li ZX,Guo XG. Pooled analysis of the Xpert MTB/RIF assay for diagnosingtuberculous meningitis. Biosci Rep.2019 Nov 28. pii: BSR20191312 Bini Estela ISABEL and Hernandez Pando ROGELIO Pathogenesis and Immune Response in Tuberculosis Meningitis. Malays J Med...